Amino acid

L-Glutamine

Amino acid studied for intestinal lining support, recovery during heavy training, immune support. How it works, the dose and timing studied, what it interacts with, and the research behind the grade.

Grade C evidence early: mostly mechanism or small studies
All compounds
Best for Intestinal lining support, Recovery during heavy training, Immune support
Typical dose 5–10 g daily
Timing Any time; often taken on an empty stomach or post-exercise
Category Amino acid
How it works

What it is and the mechanism

The most abundant free amino acid in the body and a primary fuel for enterocytes and immune cells. It supports gut barrier integrity, though performance and muscle-building claims in well-fed individuals are weakly supported.

Dose and timing

When and how much to take

The dose below reflects the range used in published research. Match the form alongside the milligrams. Set your own wake and bed times to map the timing onto your day.

Timing visualizer

When to take L-Glutamine

Dose: 5–10 g daily. Set your own wake and bed times to map the guidance onto your day.

12a6a12p6pDAY1 dose
12 pmAnytime. Timing is flexible. Pick a slot you can keep consistent.

These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

Before you stack it

Interactions and cautions

Read these before combining this with other supplements or medication. The risk is rarely the headline, it is the interaction you did not check.

Interactions
  • Anticonvulsants, theoretical interaction via glutamate metabolism
Cautions
  • Conditionally essential; benefits are clearest under physiological stress, not in healthy trained people
  • Well tolerated
Stacking

What pairs well, and what to keep apart

Derived from shared topics, complementary categories, and the interaction list. Introduce one compound at a time so you can tell what works.

Keep apart from

No direct compound conflicts derived. Still check the interactions list above against your medication.

Explore more

Compounds in the same topics

Often considered alongside this one. Each carries its own evidence grade.