Vitamin

Niacin

Vitamin studied for nad+ and energy metabolism, lipid support, skin barrier. How it works, the dose and timing studied, what it interacts with, and the research behind the grade.

Grade A evidence strong: trials and meta-analyses agree Also known as Vitamin B3, nicotinic acid, niacinamide
All compounds
Best for NAD+ and energy metabolism, Lipid support, Skin barrier
Typical dose 14–16 mg (RDA); higher lipid doses only under supervision
Timing With food to reduce flushing
Category Vitamin
How it works

What it is and the mechanism

A precursor to NAD and NADP, coenzymes central to cellular energy production and redox reactions. Nicotinic acid also influences lipid metabolism, while niacinamide supports skin barrier function.

Dose and timing

When and how much to take

The dose below reflects the range used in published research. Match the form alongside the milligrams. Set your own wake and bed times to map the timing onto your day.

Timing visualizer

When to take Niacin

Dose: 14–16 mg (RDA); higher lipid doses only under supervision. Set your own wake and bed times to map the guidance onto your day.

12a6a12p6pDAY1 dose
1 pmWith a meal. Take alongside food to aid absorption and reduce stomach upset.

These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

Before you stack it

Interactions and cautions

Read these before combining this with other supplements or medication. The risk is rarely the headline, it is the interaction you did not check.

Interactions
  • Statins, high-dose niacin combination raises myopathy risk
  • Diabetes medications, can affect glucose
Cautions
  • High-dose nicotinic acid causes flushing and can stress the liver
  • Use therapeutic doses only with a physician
Stacking

What pairs well, and what to keep apart

Derived from shared topics, complementary categories, and the interaction list. Introduce one compound at a time so you can tell what works.

Keep apart from

No direct compound conflicts derived. Still check the interactions list above against your medication.

Explore more

Compounds in the same topics

Often considered alongside this one. Each carries its own evidence grade.