Vitamin

Nicotinamide riboside

Vitamin studied for nad+ support, mitochondrial function, healthy aging (investigational). How it works, the dose and timing studied, what it interacts with, and the research behind the grade.

Grade C evidence early: mostly mechanism or small studies Also known as NR, Niagen
All compounds
Best for NAD+ support, Mitochondrial function, Healthy aging (investigational)
Typical dose 250–500 mg daily
Timing Morning; with or without food
Category Vitamin
How it works

What it is and the mechanism

A form of vitamin B3 and NAD+ precursor. Oral NR reliably raises blood NAD+ in human trials, supporting mitochondrial and metabolic pathways, though clinical benefits beyond biomarker changes remain to be confirmed.

Dose and timing

When and how much to take

The dose below reflects the range used in published research. Match the form alongside the milligrams. Set your own wake and bed times to map the timing onto your day.

Timing visualizer

When to take Nicotinamide riboside

Dose: 250–500 mg daily. Set your own wake and bed times to map the guidance onto your day.

12a6a12p6pDAY1 dose
8 amMorning. Take early in the day.

These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

Before you stack it

Interactions and cautions

Read these before combining this with other supplements or medication. The risk is rarely the headline, it is the interaction you did not check.

Interactions
  • No well-characterized drug interactions
Cautions
  • Functional outcome data are still emerging
  • Generally well tolerated
Stacking

What pairs well, and what to keep apart

Derived from shared topics, complementary categories, and the interaction list. Introduce one compound at a time so you can tell what works.

Keep apart from

No direct compound conflicts derived. Still check the interactions list above against your medication.

Explore more

Compounds in the same topics

Often considered alongside this one. Each carries its own evidence grade.