Vitamin

Vitamin K2

Vitamin studied for calcium routing to bone, arterial health, bone density. How it works, the dose and timing studied, what it interacts with, and the research behind the grade.

Grade B evidence moderate: promising but smaller or mixed human trials Also known as Menaquinone, MK-7
All compounds
Best for Calcium routing to bone, Arterial health, Bone density
Typical dose 90–180 mcg MK-7 daily
Timing With a fat-containing meal; often paired with vitamin D3
Category Vitamin
How it works

What it is and the mechanism

Activates matrix Gla protein and osteocalcin through carboxylation, directing calcium into bone and away from arterial walls. It complements vitamin D, which raises calcium absorption but does not control where it goes.

Dose and timing

When and how much to take

The dose below reflects the range used in published research. Match the form alongside the milligrams. Set your own wake and bed times to map the timing onto your day.

Timing visualizer

When to take Vitamin K2

Dose: 90–180 mcg MK-7 daily. Set your own wake and bed times to map the guidance onto your day.

12a6a12p6pDAY1 dose
8 amMorning. Take early in the day.

These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

Before you stack it

Interactions and cautions

Read these before combining this with other supplements or medication. The risk is rarely the headline, it is the interaction you did not check.

Interactions
  • Warfarin, vitamin K antagonizes the drug; do not combine without monitoring
Cautions
  • On any vitamin K antagonist, consult a physician first
  • Otherwise well tolerated
Stacking

What pairs well, and what to keep apart

Derived from shared topics, complementary categories, and the interaction list. Introduce one compound at a time so you can tell what works.

Keep apart from

No direct compound conflicts derived. Still check the interactions list above against your medication.

Explore more

Compounds in the same topics

Often considered alongside this one. Each carries its own evidence grade.