Other

DIM

Other studied for estrogen metabolism support, hormonal balance. How it works, the dose and timing studied, what it interacts with, and the research behind the grade.

Grade C evidence early: mostly mechanism or small studies Also known as Diindolylmethane
All compounds
Best for Estrogen metabolism support, Hormonal balance
Typical dose 100–200 mg daily
Timing With a fat-containing meal
Category Other
How it works

What it is and the mechanism

A compound formed from indole-3-carbinol in cruciferous vegetables that shifts estrogen metabolism toward less potent 2-hydroxy metabolites by influencing CYP1A enzymes, supporting hormonal balance.

Dose and timing

When and how much to take

The dose below reflects the range used in published research. Match the form alongside the milligrams. Set your own wake and bed times to map the timing onto your day.

Timing visualizer

When to take DIM

Dose: 100–200 mg daily. Set your own wake and bed times to map the guidance onto your day.

12a6a12p6pDAY1 dose
12 pmAnytime. Timing is flexible. Pick a slot you can keep consistent.

These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

Before you stack it

Interactions and cautions

Read these before combining this with other supplements or medication. The risk is rarely the headline, it is the interaction you did not check.

Interactions
  • CYP1A2 and CYP3A4 substrates, may alter drug metabolism
  • Hormone therapies, theoretical interaction
Cautions
  • Hormone-sensitive conditions, consult a physician
  • Can darken urine; human evidence is limited
Stacking

What pairs well, and what to keep apart

Derived from shared topics, complementary categories, and the interaction list. Introduce one compound at a time so you can tell what works.

Keep apart from

No direct compound conflicts derived. Still check the interactions list above against your medication.

Explore more

Compounds in the same topics

Often considered alongside this one. Each carries its own evidence grade.