Other

Sodium bicarbonate

Other studied for high-intensity buffering, anaerobic capacity, reduced fatigue. How it works, the dose and timing studied, what it interacts with, and the research behind the grade.

Grade B evidence moderate: promising but smaller or mixed human trials Also known as Baking soda
All compounds
Best for High-intensity buffering, Anaerobic capacity, Reduced fatigue
Typical dose 0.2–0.3 g/kg body weight
Timing 60–180 minutes before exercise, often split to limit GI upset
Category Other
How it works

What it is and the mechanism

Raises blood bicarbonate, increasing the extracellular buffering of hydrogen ions produced during high-intensity exercise. This delays the pH-related fatigue that limits efforts of one to seven minutes.

Dose and timing

When and how much to take

The dose below reflects the range used in published research. Match the form alongside the milligrams. Set your own wake and bed times to map the timing onto your day.

Timing visualizer

When to take Sodium bicarbonate

Dose: 0.2–0.3 g/kg body weight. Set your own wake and bed times to map the guidance onto your day.

12a6a12p6pDAY2 doses
7 amMorning dose. Take the first portion after waking.
9 pmEvening dose. Take the second portion in the evening.

These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

Before you stack it

Interactions and cautions

Read these before combining this with other supplements or medication. The risk is rarely the headline, it is the interaction you did not check.

Interactions
  • Sodium-restricted conditions, high sodium load matters
  • Medications affected by stomach pH, separate timing
Cautions
  • GI distress is common; trial it in training first
  • Hypertension or kidney disease, the sodium load is significant
Stacking

What pairs well, and what to keep apart

Derived from shared topics, complementary categories, and the interaction list. Introduce one compound at a time so you can tell what works.

Keep apart from

No direct compound conflicts derived. Still check the interactions list above against your medication.

Explore more

Compounds in the same topics

Often considered alongside this one. Each carries its own evidence grade.