Vitamin

Thiamine

Vitamin studied for carbohydrate metabolism, nerve function, energy production. How it works, the dose and timing studied, what it interacts with, and the research behind the grade.

Grade A evidence strong: trials and meta-analyses agree Also known as Vitamin B1
All compounds
Best for Carbohydrate metabolism, Nerve function, Energy production
Typical dose 1.1–1.2 mg (RDA); higher to correct deficiency
Timing Any time; with or without food
Category Vitamin
How it works

What it is and the mechanism

A B-vitamin whose active form is a cofactor for enzymes in glucose metabolism and ATP production, including pyruvate dehydrogenase. Deficiency impairs energy metabolism and nerve function.

Dose and timing

When and how much to take

The dose below reflects the range used in published research. Match the form alongside the milligrams. Set your own wake and bed times to map the timing onto your day.

Timing visualizer

When to take Thiamine

Dose: 1.1–1.2 mg (RDA); higher to correct deficiency. Set your own wake and bed times to map the guidance onto your day.

12a6a12p6pDAY1 dose
12 pmAnytime. Timing is flexible. Pick a slot you can keep consistent.

These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

Before you stack it

Interactions and cautions

Read these before combining this with other supplements or medication. The risk is rarely the headline, it is the interaction you did not check.

Interactions
  • Loop diuretics, can deplete thiamine
  • Heavy alcohol use, impairs absorption
Cautions
  • Water-soluble; toxicity is rare
  • Higher needs in heavy drinkers and after bariatric surgery
Stacking

What pairs well, and what to keep apart

Derived from shared topics, complementary categories, and the interaction list. Introduce one compound at a time so you can tell what works.

Keep apart from

No direct compound conflicts derived. Still check the interactions list above against your medication.

Explore more

Compounds in the same topics

Often considered alongside this one. Each carries its own evidence grade.