Other

Phosphatidylserine

Other studied for memory and attention, cortisol blunting, stress recovery. How it works, the dose and timing studied, what it interacts with, and the research behind the grade.

Grade B evidence moderate: promising but smaller or mixed human trials Also known as PS
All compounds
Best for Memory and attention, Cortisol blunting, Stress recovery
Typical dose 100–300 mg daily
Timing With meals; evening dosing may help stress-related sleep
Category Other
How it works

What it is and the mechanism

A phospholipid concentrated in neuronal membranes that supports cell signaling and neurotransmitter release. It may blunt exercise- and stress-induced cortisol and support memory in older adults.

Dose and timing

When and how much to take

The dose below reflects the range used in published research. Match the form alongside the milligrams. Set your own wake and bed times to map the timing onto your day.

Timing visualizer

When to take Phosphatidylserine

Dose: 100–300 mg daily. Set your own wake and bed times to map the guidance onto your day.

12a6a12p6pDAY1 dose
10 pmBefore bed. Take roughly 30 to 60 minutes before lights out.

These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

Before you stack it

Interactions and cautions

Read these before combining this with other supplements or medication. The risk is rarely the headline, it is the interaction you did not check.

Interactions
  • Anticholinergic and Alzheimer’s drugs, theoretical interaction
  • Anticoagulants, possible additive effect
Cautions
  • Most modern products are soy- or sunflower-derived
  • Generally well tolerated
Stacking

What pairs well, and what to keep apart

Derived from shared topics, complementary categories, and the interaction list. Introduce one compound at a time so you can tell what works.

Keep apart from

No direct compound conflicts derived. Still check the interactions list above against your medication.

Explore more

Compounds in the same topics

Often considered alongside this one. Each carries its own evidence grade.