Human trials and animal studies kept separate, legal status dated, and no products for sale. Plus a free daily briefing on new trials and FDA changes.
New trials, regulatory changes, one peptide broken down. Every claim cited.
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Grade A means an approved drug or several human randomized trials. Grade D means the evidence stops at cells and animals. Most popular research peptides sit at C or D.
37 of them are on the WADA prohibited list.
| Peptide | Evidence | Legal status |
|---|---|---|
| Semaglutide A once-weekly GLP-1 receptor agonist approved for type 2 diabetes, obesity, heart risk, kidney disease and fatty liver disease. | A Evidence | FDA-approved |
| Tirzepatide A once-weekly GIP and GLP-1 dual agonist approved for type 2 diabetes, heart risk in diabetes, obesity and sleep apnea. | A Evidence | FDA-approved |
| Retatrutide An investigational once-weekly GIP, GLP-1 and glucagon triple agonist from Eli Lilly, in late phase 3 for obesity. Not approved. | A Evidence | In clinical trials WADA prohibited |
| BPC-157 A 15-amino-acid synthetic peptide studied mostly in rats for tendon, muscle and gut healing. Human data is a handful of tiny pilot studies. | C Evidence | In clinical trials WADA prohibited |
| TB-500 A 7-amino-acid piece of thymosin beta-4 sold for injury recovery. No completed human study has tested it; a small heart trial began in 2026. | D Evidence | In clinical trials WADA prohibited |
| GHK-Cu A three-amino-acid copper peptide found in human blood, used in skin creams and studied for wound healing; injected use is untested. | B Evidence | Research chemical WADA prohibited |
| CJC-1295 A lab-modified version of the hormone that tells the pituitary to release growth hormone. Never approved; human data stop at dosing studies. | B Evidence | Research chemical WADA prohibited |
| Ipamorelin A five-amino-acid ghrelin-receptor agonist that releases growth hormone. Its only efficacy trial, for post-surgery gut paralysis, failed. | B Evidence | Research chemical WADA prohibited |
| PT-141 (Bremelanotide) A melanocortin receptor agonist, sold as Vyleesi, FDA-approved in 2019 for low sexual desire in premenopausal women. | A Evidence | FDA-approved |
| Thymosin Alpha-1 A 28-amino-acid thymus peptide sold as Zadaxin in dozens of countries for hepatitis B; not approved in the US, mixed trial results. | B Evidence | Approved outside US |
Each hub ranks its peptides by evidence and splits the ones tested in people from the ones tested only in animals or cells.
Dated, sourced, and checked against the agency page where one exists. The legal-status guide carries the full timeline.
The Pharmacy Compounding Advisory Committee recommended adding BPC-157 to the list of bulk substances pharmacies may compound from. The vote does not bind the FDA, and it does not make BPC-157 legal to compound.
Source: trade press reports of the meeting What the vote does and does not changeFDA now lists BPC-157, TB-500, CJC-1295, KPV and MOTS-c as nominations that were withdrawn. GHRP-2, GHRP-6, ipamorelin, kisspeptin-10 and MK-677 remain in Category 2.
Source: FDA, 503A Category 2 list Read the legal-status guideThe FDA approved orforglipron (Foundayo) for chronic weight management. It is a small molecule, not a peptide, and it is taken by mouth once a day.
Source: FDA approval, reported by Healio See it in the GLP-1 guideThe agency said it would restrict the GLP-1 ingredients used in mass-marketed compounded drugs. The semaglutide and tirzepatide shortages that allowed compounding ended in 2025.
Source: FDA press release Compounding timelineA vial labeled in mg, a draw written in mcg, a syringe marked in units. Most mixing errors start there. These tools show the arithmetic step by step. They give numbers, not dosing advice.
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The studies on each marker that is out of range, graded by evidence. Take them to your doctor.
Each hub is a destination: deep guides, evidence reviews, calculators, and every issue tagged to it.
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Try the Lab ReaderEvery supplement graded by the human trials behind it, with dosing ranges, mechanisms and interaction flags, all sourced.
| Compound | Best for | Evidence | Typical dose |
|---|---|---|---|
 Magnesium glycinate | Sleep quality | B | 200–400 mg before bed |
 Ashwagandha | Stress & cortisol | B | 300–600 mg daily |
 L-Theanine | Calm focus | B | 100–200 mg |
| Reishi | Relaxation | C | 1–1.5 g extract |
| Apigenin | Sleep onset | C | 50 mg |
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Each claim links to the study or agency page it came from, and a second editor checks it before it goes up.
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